Palace can do a smash-and-grab raid at United
Jose Mourinho is focused solely on Wednesday's Europa League final against Ajax and won't be too concerned about the outcome of this game.
The match is a great opportunity for United's youngsters to announce themselves in the Premier League but they face a steep learning curve against a Palace side who are playing to finish as high as possible.
1pt 7-4 bet365, BoyleSports, Ladbrokes
Several youngsters will be given their chance as Jose Mourinho rests senior men for the Europa League final. Paul Pogba and Eric Bailly will start and Timothy Fosu-Mensah returns from injury.
Andros Townsend (Achilles) is sidelined but James Tomkins (ankle) could return. Yohan Cabaye (foot) and Scott Dann (knee) are doubts and Mamadou Sakho, Connor Wickham, Pape Souare are out.
Manchester United have not won any of their last five league fixtures.