Indianapolis at Arizona betting tips and NFL predictions

Free American football tips, best bets and analysis for Indianapolis Colts at Arizona Cardinals in Week 16 of the NFL.

Where to watch

Sky Sports NFL, 1.15am Saturday night

Best bet

Indianapolis Colts
2pts Evs Paddy Power

Match preview

Indianapolis made a statement when they ended New England’s seven-game winning streak last time out and they can keep up their strong run of form by winning in Arizona on Christmas night.

The Colts lost four of their first five games this season after being hit by some early injuries, but they have won seven of their last nine games.

There was no fluke about their 27-17 defeat of the Patriots, and running back Jonathan Taylor has been one of the stars of the 2021 season.

Playing the 10-4 Cardinals next is a great fixture to guard against any complacency, and the Colts can’t afford to throw it all away now that one-time runaway AFC South leaders Tennessee are just one game ahead and are starting to struggle.

Arizona’s 7-0 start to the season is fading into the distance and they have lost four of their last seven games. Sunday’s alarming 30-12 defeat to the 2-11-1 Detroit Lions was a sign that all is not well with the Cardinals’ Super Bowl challenge.

Arizona allowed Lions’ fourth-choice running back Craig Reynolds to rush for 112 yards last week, so Taylor could have another big performance in him, and the Cards’ aerial attack is weakened by the absence of the injured DeAndre Hopkins.

The lowdown

Venue State Farm Stadium, Glendale, Arizona
Surface Grass
Weather Indoors
Vegas handicap Indianapolis +1
Vegas points line 49

Key stat

Indianapolis have covered the handicap in eight of their last 11 games.

Not got a bet365 account? Bet £10 & get £50 in free bets

Open account offer. Minimum deposit requirement. Free Bets are paid as bet credits and are available for use upon settlement of bets to value of qualifying deposit. Minimum odds, bet and payment method exclusions apply. Returns exclude bet credits stake. Time limits and T&Cs apply.

MORE FREE BETS

Pickswise is the #1 destination for US sports betting, covering the NFL, NBA, MLB and more in unrivalled detail.

For all your US sports betting needs, make sure to check out Pickswise, the home of stateside picks, predictions and odds.