Wednesday football tips: Manchester United and Liverpool in action on busy night

Manchester United resume their Champions League campaign with a trip to Atletico Madrid in the first leg of their last-16 tie and there are three important Premier League fixtures on Wednesday.

Title contenders Liverpool are aiming to keep the pressure on leaders Manchester City with a home win over Leeds while Burnley host Tottenham, who shocked the Citizens on Saturday, and Watford face Crystal Palace.

Today's best accumulator bets

Bets to be placed by 7.45pm Wednesday

Stoke to beat Luton

Liverpool to beat Leeds

Ajax to beat Benfica

Manchester United to beat Atletico Madrid

Click here to find out why we fancy this 12-1 fourfold

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Atletico Madrid v Manchester United

BT Sport 2, 8pm Wednesday

Atletico Madrid's defence has been uncharacteristically leaky this season and Manchester United have the attacking quality to inflict Atleti's fourth defeat in seven home games.

Click here to read the full preview

Best bet
Manchester United draw no bet

Benfica v Ajax

BT Sport 3, 8pm Wednesday

Ajax won all six of their Champions League group games and they can maintain their perfect record with a first-leg win over last-16 opponents Benfica, whose ageing defenders could struggle against their pacy visitors.

Click here to read the full preview

Best bet
Ajax

Bet of the day

Under 2.5 goals in Sheffield United v Blackburn
Sky Sports Football & Main Event, 7.45pm Wednesday

Sheffield United have kept six clean sheets in their last eight Championship matches and a low-scoring contest looks likely when they host Blackburn, who drew 0-0 at West Brom last time out and are missing injured top scorer Ben Brereton Diaz.

Click here to read the full preview

Best cards bet of the day

Atletico Madrid v Manchester United

Manchester United midfielder Scott McTominay has been booked in his last three Premier League appearances and the Scotland international could be in the thick of the battle against an uncompromising Atletico side.

Click here for Dan Childs's Atletico Madrid v Manchester United Bet Builder

Best bet
Scott McTominay to be shown a card