Chelsea can pile pressure on Saints boss Pellegrino
Kick-off 3pm Saturday
The top eight was the pre-season target for Saints but they might have to be factored into the relegation equation.
They are only four points clear of the drop zone and three of their next four games are against big-six clubs.
Chelsea brushed aside Huddersfield on Tuesday and should do something similar to Southampton.
Chelsea-Chelsea double result
1pt 15-13 Ladbrokes
Alvaro Morata (back) is in contention but David Luiz (knee) misses out.
Changes could be made following the 4-1 loss at home to Leicester with Wesley Hoedt, Nathan Redmond and James Ward-Prowse pushing for recalls.
Southampton have not kept a clean sheet in their last eight games.
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