Bilbao and Betis can both find the net
Celta Vigo, nicely housed mid-table, have an upcoming Europa League semi-final against Manchester United to focus on, so could be forgiven for going through the motions in Seville.
The hosts are pretty much unbeatable at home and will be hard to beat as they endeavour to chase down Atletico for third place.
Steve Davies's recommendation
3pts 2-5 Betway
Seville have lost only one of 16 home league games this season.
Athletic continue their pursuit of Europa League qualification and, as ever, they will be a tough nut to crack on home soil at their San Mames fortress when Real Betis make the long trek to Bilbao.
Sixth spot will guarantee Athletic a European place for next term, although it would drop down to seventh should Barcelona beat Alaves in the Copa del Rey final.
Either way, Athletic are well set following Monday's tense 1-0 success at Eibar and only Real Madrid and Barcelona have tasted success at San Mames this season.
Raul Garcia popped up with the only goal at Eibar, while Aritz Aduriz and Inaki Williams are also threats, and Athletic are justifiably strong favourites.
However, little is being given away in the match prices and a better bet could come be to back both teams to score.
Athletic have collected only two clean sheets in their last nine at home and even relegation-threatened sides such as Sporting Gijon and Granada managed to hit the target.
Betis are better than both of those and have managed to score in 11 of their last 12 matches.
The visitors have also scored in their last seven away trips and since Christmas only Champions League semi-finalists Atletico Madrid have managed to shut out Betis on their travels.
Even then Betis managed six shots on target but they have only one clean sheet in 17 away matches this season.
Mark Langdon's recommendation
Both teams to score
1pt 30-29 188Bet
Real Betis have won their last two games, the only time they have won back-to-back matches this season.