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New study shows 'speed gene' is main determinant of optimum race distance

Research also warns that stayers face serious threat of extinction

Emmeline Hill: associate professor of equine science at University College Dublin and chief science officer at Plusvital
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The 'speed gene' is the main determinant of why some horses are born sprinters and others are born stayers.

That is according to a new study led by UCD associate professor of equine science Emmeline Hill, who is also chief science officer at Irish equine science company Plusvital.

The research, published in the Equine Veterinary Journal this week, analysed the genetics and race records of over 3,000 thoroughbred racehorses who raced in Europe, Australia, South Africa and the US.

It found that the myostatin gene or 'speed gene' is the almost singular genetic determinant of a horse's optimum race distance.

The notion of a single gene being responsible for a performance trait in thoroughbreds has previously been challenged. However, Professor Hill said the new study ended any dispute over the central role of the 'speed gene'.

"We have replicated and validated our original research findings on a massively larger scale," said Hill.

"The power in the numbers has shown that the association of the 'speed gene' with race distance is as statistically strong as the most highly genetically influenced traits in humans, including eye colour and the probability of an individual going bald."

The study found that in Europe more than 83 per cent of 'speed gene' type C:C (sprint) horses had an optimum race distance of a mile or shorter and more than 89 per cent of T:T (staying) horses performed best over distances greater than a mile (fig 1). 

The trend was consistent across all race regions but the race pattern influenced the distribution of the 'speed gene' types.

In Australia, where there is an emphasis on early two-year-old speed, there were almost twice as many C:C horses among elite winners in the population compared to Europe and North America (46 per cent compared to 26 per cent and 28 per cent). There was almost seven times as many C:Cs as T:Ts within the Australian population.

Fig 1: infographic showing 89 per cent of European horses with the T:T (staying) speed gene perform best over further than a mile

The main differences between sprinters and staying-type horses has been shown to be caused by a mutation in the 'speed gene' that alters the rate of muscle growth and fibre-type differences in the muscle. Although myostatin is the most important gene, the latest research has also identified additional genes which have moderate effects on the staying ability of a horse.

Professor Hill said the application of genetics to decision making about how horses were trained and raced is transforming the industry.

Hill said: "Our results clearly show that using evidence-based science will lead to more accurate placing of horses in races that are best suited to their genetic potential. Horses are a product of their inherited genetic characteristics as well as the environment.

"The management of the horse is key in any horse's success, but DNA differences are the undisputed differences that make them individuals. This genetic information is leading to horses being trained and raced for their genetic potential and is providing a clear economic advantage to owners and trainers."

Stayers facing threat of extinction

The research also warns that horses who perform best over longer distances are at serious threat of extinction in the global population.

"Since there is just one gene that is a major player in the sprinting versus staying stakes, it is extremely vulnerable to selection pressures," said Hill.

"This has been recognised by the concern in the industry over the potential reduction in genetic diversity by favouring precocious, commercially attractive horses.

"This concern is well justified - the staying type is at serious threat of extinction in the global population. T:T (staying) types make up less than 17 per cent of elite race winners in Britain and Ireland and less than 7 per cent of the Australian elite-winning population. This is a complete reversal from the picture of genetics of the thoroughbred 150 years ago.

"We do not operate our testing services in the sales environment which could further accelerate this trend. However, it is essential that the industry incentivises the breeding and racing of stayers to reduce the pressure to breed for the sales ring."


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